کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5831480 1122153 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Phenolics from Bidens bipinnata and their amylase inhibitory properties
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Phenolics from Bidens bipinnata and their amylase inhibitory properties
چکیده انگلیسی

A new chlorinated flavonoid, 3, 6, 8-trichloro-5, 7, 3′, 4′-tetrahydroxyflavone (1), a new biscoumaric acid derivative, 4-O-(2″, 3″-O-diacetyl-6″-O-p-coumaroyl-β-d-glucopyranosyl)-p-coumaric acid (2), and 8, 3′, 4′-trihydroxyflavone-7-O-β-d-glucopyranoside (3) together with twenty-four known compounds (4-27) were isolated from the whole plant of Bidens bipinnata. All chemical structures were established on the basis of UV-, MS- and NMR (1H, 13C, 1H-1H COSY, HMQC and HMBC) spectroscopic data. Some of the isolated compounds were tested for the inhibition of α-amylase. The result showed that isookanin (6) was a potent inhibitor of α-amylase (IC50 = 0.447 mg/ml).

A new chlorinated flavonoid, 3, 6, 8-trichloro-5, 7, 3′, 4′-tetrahydroxyflavone (1), a new biscoumaric acid derivative, 4-O-(2″, 3″-O-diacetyl-6″-O-p-coumaroyl β-d-glucopyranosyl)-p-coumaric acid (2), and 8, 3′, 4′-trihydroxyflavone-7-O-β-d-glucopyranoside (3) together with twenty-four known compounds (4-27) were isolated from the whole plant of Bidens bipinnata. Some of the isolated compounds were tested for the inhibition of α-amylase.96

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 83, Issue 7, October 2012, Pages 1169-1175
نویسندگان
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