The effects of Betula platyphylla bark on amyloid beta-induced learning and memory impairment in mice

- BPB-316 significantly attenuated Aβ1-42-induced memory impairment by activating the CREB-BDNF pathway.
- BPB-316 also inhibited the elevation of β-secretase activity accompanying the reduced Aβ1-42 levels in the hippocampus.
- BPB-316 significantly suppressed the AChE activity and recovered the content of GSH in the hippocampus.