کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5850814 | 1561781 | 2014 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Establishment of Reference Doses for residues of allergenic foods: Report of the VITAL Expert Panel
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش تغذیه
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![عکس صفحه اول مقاله: Establishment of Reference Doses for residues of allergenic foods: Report of the VITAL Expert Panel Establishment of Reference Doses for residues of allergenic foods: Report of the VITAL Expert Panel](/preview/png/5850814.png)
چکیده انگلیسی
In 2011, an expert panel was assembled to establish appropriate Reference Doses for allergenic food residues as a part of the VITAL (Voluntary Incidental Trace Allergen Labeling) program of The Allergen Bureau of Australia & New Zealand (ABA). These Reference Doses would guide advisory labeling decisions for use on food labels. Individual NOAELs and LOAELs were obtained from clinical challenges of food-allergic subjects. Statistical dose-distribution models (log-normal, log-logistic, Weibull) were applied to the individual NOAELs and LOAELs for each allergenic food. The Reference Doses, in terms of mg of total protein from the allergenic food, were based upon either the ED01 (for peanut, cow's milk), the 95% lower confidence interval of the ED05 (for wheat, soybean, cashew, shrimp, sesame seed, mustard, and lupine), or both (egg, hazelnut) using all appropriate statistical dose-distribution models. Reference Doses were established for 11 allergenic foods ranging from 0.03Â mg for egg protein to 10Â mg for shrimp protein. Reference Doses were not established for fish or celery due to poor model fits with existing data. Reference Doses were not established for other tree nuts beyond hazelnut and cashew because of the absence of data on NOAELs and LOAELs from individual subjects.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food and Chemical Toxicology - Volume 63, January 2014, Pages 9-17
Journal: Food and Chemical Toxicology - Volume 63, January 2014, Pages 9-17
نویسندگان
Steve L. Taylor, Joseph L. Baumert, Astrid G. Kruizinga, Benjamin C. Remington, Rene W.R. Crevel, Simon Brooke-Taylor, Katrina J. Allen, The Allergen Bureau of Australia & New Zealand The Allergen Bureau of Australia & New Zealand, Geert Houben,