Artichoke induces genetic toxicity in the cytokinesis-block micronucleus (CBMN) cytome assay

► Extracts from Cynara scolymus are mutagenic in CHO cells. ► Cynara scolymus L. LE induced chromosomal mutations. ► The 24-h treatment increased MNi frequency, when compared to the 1-h treatment. ► No significant increase was observed for NPBs and NBUDs.