Dermal exposure to methamphetamine hydrochloride contaminated residential surfaces

► In vitro percutaneous absorption of [14C]-meth HCl from contaminated aqueous solution or solid surface. ► Evaluated pH effects on volatility and stability of [14C]-meth HCl. ► Smooth, dense surfaces favor [14C]-meth HCl retention and transfer. ► When the pH exceeds 4, [14C]-meth HCl likely converts to its volatile freebase form. ► Skin surface pH can be a critical factor affecting the dermal absorption rate.