Indole-3-carbinol inhibits LPS-induced inflammatory response by blocking TRIF-dependent signaling pathway in macrophages

- We evaluated the anti-inflammatory effects of Indole-3-carbinol in vitro and in vivo.
- Indole-3-carbinol attenuated TRIF-dependent signaling pathway from LPS stimulation.
- Indole-3-carbinol can be developed as an effective anti-inflammatory compound.