Comparative analysis on the effect of Lycopersicon esculentum (tomato) in reducing cadmium, mercury and lead accumulation in liver

► Lycopersicon esculentum (tomato) reduces tissue heavy metal burden/toxicity in the liver. ► Post-treatment offered more hepatoprotective effect to cadmium and mercury but not to lead. ► Pre-treatment offered more hepatoprotective effect to lead (Pb). ► Hepatoprotective effect was more to cadmium followed by mercury and least to lead accumulation. ► Nutrient affected the processes of uptake, assimilation and elimination of these metals in a time dependant manner.