Toxicological effects of red wine, orange juice, and other dietary SULT1A inhibitors via excess catecholamines

► Common foods contain natural substances that inhibit human SULT1A in vivo. ► Dietary SULT1A inhibition causes migraines in susceptible people. ► SULT1A inhibition may cause “holiday heart” and diabetes in susceptible people. ► There is probably a genetic component to susceptibility to SULT1A inhibition. ► Analysis of using recreational alcohols must account for SULT1A inhibition.