Carcinogenic activity of benzo[a]pyrene in a 2 year oral study in Wistar rats

► There is high human oral exposure to PAHs. ► Benzo[a]pyrene can be used as a representative of PAHs. ► Benzo[a]pyrene was tested in an oral carcinogenicity study in rats. ► Benzo[a]pyrene is carcinogenic in rats, inducing tumours in liver and forestomach.