Determination and study on dissipation of 1-naphthylacetic acid in garlic and soil using high performance liquid chromatography-tandem mass spectrometry

A simple, quick and reliable analytical method for the determination of 1-naphthylacetic acid in garlic and soil has been developed in this study. The residual levels and dissipation rates of 1-naphthylacetic acid in garlic and soil were determined by high performance liquid chromatography-tandem mass spectroscopy (HPLC-MS/MS). The limit of quantification (LOQ) of the developed method was 0.005 mg/kg. The half-lives of 1-naphthylacetic acid in garlic plants and soil were 0.80-1.4 days and 0.94-2.0 days, respectively. The final residues of 1-naphthylacetic acid in garlic, garlic sprout and soil could not be detected and were all below 0.05 mg/kg (the MRL of EU). Results of the ultimate residues in garlic and soil showed that this pesticide is safe to be used under the recommended dosages.

► Develop modified QuEChERS method to determine NAA in garlic and soil first. ► Analytes were analyzed by HPLC-MS/MS. ► Dissipation dynamics of NAA in garlic and oil were studied. ► Sample pretreatment, cleanup, and HPLC-MS/MS conditions were optimized.