Immediate Changes After Manual Therapy in Resting-State Functional Connectivity as Measured by Functional Magnetic Resonance Imaging in Participants With Induced Low Back Pain

These results suggest that MTs (chiropractic spinal manipulation, spinal mobilization, and therapeutic touch) have an immediate effect on the FC between brain regions involved in processing and modulating the pain experience. This suggests that neurophysiologic changes after MT may be an underlying mechanism of pain relief.