کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5871003 1141808 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Original researchPatients newly diagnosed with clinical type 2 diabetes mellitus but presenting with HbA1c within normal range: 19-Year mortality and clinical outcomes
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Original researchPatients newly diagnosed with clinical type 2 diabetes mellitus but presenting with HbA1c within normal range: 19-Year mortality and clinical outcomes
چکیده انگلیسی

AimsTo investigate whether long-term mortality or clinical outcomes differed between patients diagnosed with type 2 diabetes mellitus and presenting with HbA1c within or above normal range at time of diagnosis.MethodsData were from a population-based sample of 1136 individuals with newly diagnosed type 2 diabetes mellitus. The diagnosis was confirmed with a single fasting whole blood/plasma glucose ≥7.0/8.0 mmol/l. The median time from day of diagnosis until end of follow up was 18.8 years. Patients were grouped according to normal HbA1c and elevated HbA1c at diagnosis. The effect of elevated HbA1c on a number of clinical outcomes and all-cause mortality was assessed in Cox regression models.ResultsAt diagnosis, 97 patients (8.5%) had an HbA1c level within normal range. Age (mean (SD)) at diagnosis was 64.5 (11.5) years. Both unadjusted and adjusted hazard ratios for the effect of HbA1c on mortality and other outcomes were not statistically significant.ConclusionsPatients who are diagnosed with type 2 diabetes mellitus by means of elevated fasting whole blood/plasma glucose but have HbA1c within reference range at diagnosis do not seem to have a relatively benign long-term clinical course. Therefore new diagnostic procedures should preferably be able to identify these individuals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Primary Care Diabetes - Volume 7, Issue 1, April 2013, Pages 33-38
نویسندگان
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