کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5877583 | 1145983 | 2012 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Review ArticleResistance to antiplatelet treatment: The clinical relevance of platelet function assays Review ArticleResistance to antiplatelet treatment: The clinical relevance of platelet function assays](/preview/png/5877583.png)
In cardiology, functional platelet activity is not routinely monitored. Platelet function assays should be able to identify patients with high residual platelet reactivity (HPR). High on-treatment platelet reactivity is apparent risk factor for atherothrombosis, however not the only one. Since there are many contributing factors (platelet activation, endothelial dysfunction, and plaque rupture) influencing atherothrombosis. Antiplatelet treatment is targeted to diminish platelet activation. The unique pharmacodynamics, pharmacokinetics of each agent and the pharmacogenetic profile of the recipient need to be taken into consideration. The aim of this review article is to summarize current knowledge of platelet function monitoring and its usefulness in clinical cardiology.
Journal: Cor et Vasa - Volume 54, Issue 5, SeptemberâOctober 2012, Pages e305-e313