کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5882879 1149772 2014 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nodular Lymphocyte Predominant Hodgkin Lymphoma: Biology, Diagnosis and Treatment
ترجمه فارسی عنوان
لنفوم هوچکین غالب لنفوسیت مدفوع: زیست شناسی، تشخیص و درمان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی
Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is an uncommon variant of classical Hodgkin lymphoma. It is characterized histologically by presence of lymphohistiocytic cells which have B-cell phenotype, are positive for CD19, CD20, CD45, CD79a, BOB.1, Oct.2, and negative for CD15 and CD30. Patients often present with early stage of disease and do not have classical B symptoms. The clinical behavior appears to mimic that of an indolent non-Hodgkin lymphoma more than that of classical Hodgkin disease. The purpose of the present report is to define the biology of NLPHL, review its clinical presentation, and summarize the available clinical data regarding treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Lymphoma Myeloma and Leukemia - Volume 14, Issue 4, August 2014, Pages 261-270
نویسندگان
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