کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5886427 1150935 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Metabolism/GlucoseStress hyperglycemia may not be harmful in critically ill patients with sepsis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
پیش نمایش صفحه اول مقاله
Metabolism/GlucoseStress hyperglycemia may not be harmful in critically ill patients with sepsis
چکیده انگلیسی

BackgroundStress hyperglycemia (SH) is commonly seen in critically ill patients. It has been shown to be associated with adverse outcomes in some groups of patients. The effects of SH on critically ill patients with sepsis have not been well studied. We aimed to evaluate the effects of SH in critically ill patients with sepsis.MethodsIn this retrospective study, patients with sepsis admitted to intensive care unit (ICU) over a 5-year period were included.ResultsOf 297 patients, 204 (68.7%) had SH during the study period. The mean blood glucose level in patients with SH was 8.7 mmol/L compared with 5.9 mmol/L in those without SH (P < .05). There were no statistically significant differences in age; sex; sepsis severity; cardiovascular, respiratory, and renal comorbidities; requirement of mechanical ventilation; inotropes; and Acute Physiology, Age, and Chronic Health Evaluation III and Simplified Acute Physiology 2 scores on ICU admission. Intensive care unit mortality was significantly lower in patients who had SH. The median duration of ICU and hospital length of stay was longer in patients with SH. On logistic regression analysis, the presence of SH was associated with reduced ICU mortality. Subgroup analysis revealed SH to be protective in patients with septic shock.ConclusionStress hyperglycemia may not be harmful in critically ill patients with sepsis. Patients with SH had lower ICU mortality.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Critical Care - Volume 27, Issue 2, April 2012, Pages 153-158
نویسندگان
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