Effect of the fungal immunomodulatory protein FIP-fve on airway inflammation and cytokine production in mouse asthma model

► FIP-fve treatment suppressed the airway hyperresponsiveness. ► FIP-fve decreased the infiltrating inflammatory cells and Th2 cytokines. ► FIP-fve reduced OVA-specific IgE levels in serum. ► Oral FIP-fve might possess an alternative therapy for allergic airway diseases.