Adipose tissue-derived factors as potential biomarkers in cachectic cancer patients

► Changes in white adipose tissue adipokines may be associated with cancer cachexia. ► Subcutaneous and visceral depots are affected by cachexia in different manner. ► The subcutaneous depot seems to be an important source of adipokines in cancer cachexia. ► The results open new perspectives for the diagnosis and grading of cachexia.