IL-6-174 GÂ >Â C and MMP-9-1562 CÂ >Â T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients

► Evaluation of IL-6 and MMP-9 polymorphisms in cancer patients DVT+ and DVT−. ► Changes in plasma levels of IL-6 and MMP-9 in cancer patients DVT+ and DVT−. ► We show the significant role of the cytokine IL-6 in MMP-9 activation. ► IL-6 and MMP-9 polymorphisms may be useful in cancer patients management.