Lack of association between macrophage migration inhibitory factor gene promoter (−173 G/C) polymorphism and childhood Henoch-Schönlein purpura in Turkish patients

► Association between −173 G/C SNP of MIF gene and HSP risk is suggested. ► PCR-RFLP method and sytatistical risk assessment are used. ► No association is obtained between GC+CC genotype/C allele and HSP development. ► Genetic association between the MIF gene and HSP pathogenesis is not detected. ► Search for possible candidate genes in HSP in various ethnicities is required.