BLyS expression and JNK activation may form a feedback loop to promote survival and proliferation of multiple myeloma cells

► JNK signaling pathway is activated in MM cells. ► JNK signaling pathway regulate the expression of BLyS in MM cells. ► BLyS activate JNK signaling pathway in MM cells. ► JNK activation and BLyS expression in MM cells may form a positive feedback loop.