Cytokines as regulators of proliferation and survival of healthy and malignant peripheral B cells

► Cytokines have been shown to play a critical role in maintaining lymphocyte maintenance. ► Regulation of healthy peripheral B cells survival by BAFF, APRIL, MIF, HGF, midkine and their receptors. ► Regulation of malignant B cell survival by BAFF, APRIL, MIF, HGF, midkine and their receptors.