Analysis of CCR5 and CX3CR1 gene polymorphisms in association with unexplained recurrent miscarriages among north Indian women

► The study has been conducted on well characterized RM patients and healthy controls. ► Common polymorphisms of CCR5 and CX3CR1 were analyzed for their association with RM. ► Significant association of alleles and genotypes of CX3CR1 Val249Ile and haplotypes were observed. ► Risk of RM was modified by the presence of haplotypes T-I, M-V, G-T-I, A-T-I and A-M-V. ► We endorse inclusion of well characterized RM and matched true negative controls in such studies.