Both adiponectin and interleukin-10 inhibit LPS-induced activation of the NF-κB pathway in 3T3-L1 adipocytes

► The effects of adiponectin and IL-10 on NF-κB DNA binding activity. ► Role of TLR signaling in LPS-treated 3T3-L1 adipocytes. ► Role the adiponectin and IL-10 upon TLR signaling. ► Action alone and/or combination the adiponectin and IL-10.