Serum hematopoietic growth factors as diagnostic and prognostic markers of acute renal allograft rejection: A potential role for serum stem cell factor

► Association between hematopoietic growth factors (HGFs) and acute renal rejection. ► Stem cell factor (SCF), IL-3, flt3 ligand, G-CSF, M-CSF and GM-CSF levels increase. ► SCF amplify rejection by mediating communication between mast cells and T cells. ► SCF represent potential diagnostic and predictive biomarkers of acute rejection.