Effects of selective H.E.L.P. LDL-apheresis on plasma inflammatory markers concentration in severe dyslipidemia: Implication for anti-inflammatory response

► This brief review provides some indication on existing evidence of H.E.L.P. LDL_a effects on plasma mediators of inflammation. ► The studies on H.E.L.P. system effects on plasma inflammatory markers in severe dyslipidemia were evaluated. ► The reported inflammatory markers change is probably due to a direct/indirect effect of H.E.L.P. LDL_a. ► H.E.L.P. LDL_a induced anti-inflammatory and anti-atherogenic plasma profile.