کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5900809 1568875 2016 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stimulation of food intake after central administration of gonadotropin-inhibitory hormone is similar in genetically selected low and high body weight lines of chickens
ترجمه فارسی عنوان
تحریک مصرف غذا پس از تزریق مرکزی هورمون مهارکننده گنادوتروپین در ژنهای انتخابی کم و زیاد وزن مرغها
کلمات کلیدی
جوجه ها، مصرف غذا، هیپوتالاموس، هورمون مهارکننده گنادوتروپین،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی
Gonadotropin-inhibitory hormone (GnIH), first isolated from the brain of the Japanese quail (Coturnix japonica), when centrally administered exerts orexigenic effects in birds. However, the precise mechanisms mediating this effect are poorly understood and limited information is available on this effect in models of body weight dysfunction. Thus, the purpose of the present study was to investigate appetite-associated effects of GnIH in chicks from lines that have been selected for either low or high body weight, and are anorexic or become obese, respectively. Central GnIH injection increased food intake in both lines with a similar magnitude of response. There was no effect on water intake. Hypothalamic GnIH mRNA was greater in the low than high weight lines and was greater in the fasted than fed chicks. GnIH receptor mRNA was similarly expressed in both lines, and was greater in fed than fasted chicks. Thus, although selection for body weight did not alter the effect of GnIH on feeding, fasting increased GnIH mRNA in both lines implying that it is an innate hunger factor.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General and Comparative Endocrinology - Volume 232, 1 June 2016, Pages 96-100
نویسندگان
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