The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males

► Flutamide plus finasteride suppressed sex hormones in pregnant spotted hyenas. ► Flutamide plus finasteride may have agonistic actions in pregnant spotted hyenas. ► Flutamide and finasteride did not suppress LH and androgens in male hyenas.