Neuroendocrine cells in Drosophila melanogaster producing GPA2/GPB5, a hormone with homology to LH, FSH and TSH

► The glycoprotein hormone GPA2/GPB5 is a neuroendocrine hormone in Drosophila. ► In the absence of GPA2/GPB5 survival is compromised in Drosophila. ► Drosophila GPA2/GPB5 is perhaps an antidiuretic hormone.