کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5901941 | 1156840 | 2016 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Screening for type 2 diabetes mellitus in overweight and obese subjects made easy by the FINDRISC score Screening for type 2 diabetes mellitus in overweight and obese subjects made easy by the FINDRISC score](/preview/png/5901941.png)
AimTo evaluate the use of the FINDRISC score in an overweight and obese population to predict glucose status.MethodsIn 651 overweight/obese subjects (M/F: 193/458, age 43 ± 13 y, BMI 38.2 ± 6.1 kg/m2) glucose status was tested using OGTT and HbA1c. Furthermore, the FINDRISC questionnaire and CT visceral fat (VAT) and subcutaneous fat (SAT) were examined.ResultsExactly 50.4% were found to have prediabetes and 11.1% were newly diagnosed with type 2 diabetes (T2DM) (M/F = 22.2/8.8%). Subjects without T2DM had a FINDRISC score of 11 ± 3, those with pre-DM 13 ± 4, and subjects with de novo T2DM 15 ± 5. The aROC of the FINDRISC for detecting T2DM was 0.76 (95% CI 0.72-0.82), with 13 as cutoff point.The FINDRISC score correlated with VAT (r = 0.34, p < 0.001) and VAT/SAT ratio (r = 0.39, p < 0.001). The aROC of the FINDRISC to detect excess VAT was 0.79 (95%CI 0.72-0.84).ConclusionsIn a large group of overweight and obese subjects, 50.4% were found to have pre-DM and 11.1% were newly diagnosed with T2DM. The FINDRISC score increased with worsening of glucose tolerance status and proved to be an independent predictor of T2DM status, as did HOMA-B, HOMA-S and VAT. The FINDRISC can also function as a good tool to predict visceral obesity.
Journal: Journal of Diabetes and its Complications - Volume 30, Issue 6, August 2016, Pages 1043-1049