کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5902449 1156851 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glycemic variability and diabetes retinopathy: A missing link
ترجمه فارسی عنوان
تنوع گلیسمیک و رتینوپاتی دیابت: یک پیوند گمشده
کلمات کلیدی
رتینوپاتی دیابتی، متغیر گلیسمی، هیپرگلیسمی پس از فروپاشی روده، عوارض جانبی عضلانی عوارض مکروواسیکولار،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی

Daily glucose variability, such as fasting plasma glucose fluctuation or postprandial hyperglycemia, has been proposed as contributors to diabetes-related macrovascular complications. However, its impacts on microvascular complications, such as diabetes retinopathy remain controversial. We reviewed the current evidence of the relationship between glycemic variability and diabetes retinopathy in patients with type 1 or type 2 diabetes. In general, the short-term glycemic fluctuation, either expressed as standard deviation of fasting glucose or mean glucose levels, may contribute to the development or progression of diabetic retinopathy in patients with type 2 diabetes, whereas long-term glycemic fluctuation, reflected by variation of levels of HbA1c, appeared to show a stronger association with diabetes retinopathy both in patients with type 1 and type 2 diabetes. These findings emphasize the need to reduce glycemic variability by various measures in order to reduce development and progression of diabetes retinopathy both in type 1 and type 2 diabetes patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Diabetes and its Complications - Volume 29, Issue 2, March 2015, Pages 302-306
نویسندگان
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