کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5905833 | 1159938 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Novel polymorphisms of SIX4 gene and their association with body measurement traits in Qinchuan cattle
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کلمات کلیدی
Six4body measurement traitsHip widthchest depthdNTPRFLPPICSNPsPBWQinchuan cattlehip height - ارتفاع لگنUltraviolet - اشعه فرابنفشeffective allele numbers - اعداد موثر آللmarker-assisted selection - انتخاب کمک کننده نشانگرMAS - بیشترdeoxyribonucleoside triphosphate - دز اکسید ریبونوکلئوزید تری فسفاتbody length - طول بدنwithers height - قد بلندpolymorphism information content - محتوای اطلاعات پلی مورفیسمChest circumference - محدوده قفسه سینهpolymerase chain reaction - واکنش زنجیره ای پلیمرازPCR - واکنش زنجیرهٔ پلیمرازrestriction fragment length polymorphisms - پلی مورفیسم طول قطعه قطعهSingle nucleotide polymorphisms - پلیمورفیسم تک نوکلئوتیدیSNP - چندریختی تک-نوکلئوتید
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Novel polymorphisms of SIX4 gene and their association with body measurement traits in Qinchuan cattle Novel polymorphisms of SIX4 gene and their association with body measurement traits in Qinchuan cattle](/preview/png/5905833.png)
چکیده انگلیسی
Sine oculis homeobox homolog 4 (SIX4) gene belongs to the sine oculis/SIX gene family, which includes six members in vertebrates. SIX4 gene plays a crucial role in skeletal myogenesis, and its genetic variations or deficiency may cause hypopituitarism, suggesting that SIX4 gene is a potential candidate gene affecting body measurement traits (BMTs) in animals. Herein, the objectives of this study were to identify genetic polymorphisms of bovine SIX4 gene and to analyze potential association between single nucleotide polymorphisms (SNPs) and body measurement traits in Qinchuan cattle. In the present study, we investigated polymorphisms of SIX4 gene in 426 Qinchuan cattle using DNA sequencing and polymerase chain reaction-restriction fragment length polymorphisms. Three novel SNPs were identified within bovine SIX4 gene. Associations between body measurement traits and SIX4 gene polymorphisms were investigated, and significant statistical associations were found between polymorphisms of these three SNPs and body measurement traits (PÂ <Â 0.05). Hence, based on results obtained from this study, we conjectured that SIX4 gene may have potential effects on body measurement traits in Qinchuan cattle population and could be used for marker-assisted selection.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 539, Issue 1, 10 April 2014, Pages 107-110
Journal: Gene - Volume 539, Issue 1, 10 April 2014, Pages 107-110
نویسندگان
Guoqing Wang, Song Zhang, Shengjuan Wei, Yaran Zhang, Yaokun Li, Changzhen Fu, Chunping Zhao, Linsen Zan,