MicroRNA-mRNA interaction network using TSK-type recurrent neural fuzzy network

► We extracted miRNA-mRNA interaction network from microarray data of CRC patients. ► TSK-type recurrent neural fuzzy network(TRNFN) was used to identify the interactions. ► TRNFN showed good performance in recovering known miRNA-mRNA associations. ► The approach proved successful in identifying 17 validated cancer related miRNAs. ► Focusing such miRNAs aids the development of new miRNA based anti-cancer therapies.