Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene

► Four new mRNA splice isoforms of human YAP1 gene are identified. ► Exons 4, 5 and 6 of the human YAP1 gene are differentially spliced. ► Exon 6 of the YAP1 gene appeared in evolution during the emergence of amniotes. ► Six out of eight YAP1 isoforms have disrupted leucine zippers.