First synthesis of aminonaphthoquinones derived from lawsone in a colloidal dispersion system created by a Brønsted acid-surfactant-combined catalyst in water: An environmentally friendly protocol

• First synthesis of aminonaphthoquinones derived from lawsone in a colloidal dispersion system;
• Mannich reaction of lawsone using water as solvent;
• Use of DBSA as a catalyst exploring a Brønsted acid-surfactant catalyst (BASC) concept.

Environmentally friendly one-pot protocol was developed for the first synthesis of aminonaphthoquinones derived from 2-hydroxy-1,4-naphthoquinone (lawsone) via a multicomponent Mannich reaction in aqueous media using a catalytic amount of dodecyl benzenesulfonic acid (DBSA), exploring a Brønsted acid-surfactant catalyst (BASC) concept, at room temperature.

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