Effects of curcumin on the parasite Schistosoma mansoni: A transcriptomic approach

► 2374 differentially expressed genes of which 981 were up- and 1393 downregulated. ► Among them there were components of important signaling pathways. ► Pathways involved in embryogenesis and oogenesis such as Notch and TGF-β. ► Gene networks most significantly enriched with altered genes were identified. ► Repression in these pathways could explain effects on oviposition/egg development.