A novel dual Dbp5/DDX19 homologue from Plasmodium falciparum requires Q motif for activity

▶ Plasmodium falciparum contains a homologue of Dbp5/DDX19. ▶ Biochemical characterization shows PfD66 contains nucleic acid unwinding activity. ▶ PfD66 also contains ATPase and RNA binding activities ▶ Q motif is essential for all the activities of PfD66.