Molecular characterization of cytochrome P450 CYP6B47 cDNAs and 5′-flanking sequence from Spodoptera litura (Lepidoptera: Noctuidae): Its response to lead stress

► A novel full-length P450 cDNA CYP6B47 belongs to second clade of CYP6Bs. ► We predicted multiple putative elements for transcription factors. ► The basal luciferase activitie of 5′-flanking sequence was presented. ► Expression of CYP6B47 and tolerance to the pyrethroids increased after Pb exposure.