کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5922660 1166279 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of day-night cycle on distribution of food intake and economic choice among imposed food opportunities in mice
ترجمه فارسی عنوان
اثر چرخه شبانه روزی بر توزیع مصرف غذا و انتخاب اقتصادی در میان فرصت های غذایی در موش
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
چکیده انگلیسی


- Mice fed at four 40-min opportunities per day show a sequencing of meal size.
- That sequencing is changed by phase advance or delay of light:dark Zeitgeber.
- Mice with intermittent inexpensive food eat ~ 50% from a constant costly source.
- Intake from the intermittent inexpensive food occurs only nocturnally.
- Food intake and choice in mice is highly sensitive to the light:dark Zeitgeber.

We have shown previously that mice given access to four discrete feeding opportunities (FOs) per day show a characteristic sequence of sizes across ordinal FOs. The purpose of the present experiments was to determine the relative contributions of external and internal factors on the sequencing of FO size. The external factors were the light:dark Zeitgeber and the cost of food, imposed via different fixed unit prices (FUP) in a closed operant economy, and the internal factors were signals relating to energy status including time since last food and weight loss. In the first experiment, mice were given 4 FOs spaced 4-h apart, but with the timing of the FOs relative to the Zeitgeber altered by a 4-h Zeitgeber advance or delay of the cycle. Food intake, and associated body weight, declined as price increased, but the temporal order of FO size was invariant within a Zeitgeber condition. The Zeitgeber advanced group showed clear evidence of a shift in meal sequence relating to the light:dark cycle. Thus, external factors seem to be a more important determinant of total intake and sequencing than internal factors. In the second experiment, mice were given the choice between continuous costly (CC) and intermittent inexpensive (II) food. II food was available for four-15 min intervals every 4-h, and the timing of the 15 min intervals was varied relative to the Zeitgeber cycle. In spite of a 20-fold difference in price between CC and II food, mice took approximately equal amounts from each, and all food intake took place during the dark phase. Mice consumed II food only if it was available during the dark phase. Food intake was strongly linked to the light:dark cycle, largely independent of food cost.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 164, Part A, 1 October 2016, Pages 395-399
نویسندگان
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