Daily profile in two circadian markers “melatonin and cortisol” and associations with metabolic syndrome components

► Investigate associations in circadian markers with metabolic syndrome. ► Women with MetS had less melatonin values at night than women without MetS. ► Cortisol levels toward a more flattened pattern among MetS women. ► Melatonin and cortisol amplitudes were associated with MetS score and components. ► Melatonin and cortisol circadian patterns were associated with metabolic disturbances.