کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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59249 | 1419462 | 2012 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Synthesis of 2-Amino-4,6-diarylnicotinonitriles Using Silica-Bound N-Propyl Triethylenetetramine Sulfamic Acid as a Recyclable Solid Acid Catalyst Synthesis of 2-Amino-4,6-diarylnicotinonitriles Using Silica-Bound N-Propyl Triethylenetetramine Sulfamic Acid as a Recyclable Solid Acid Catalyst](/preview/png/59249.png)
A simple and efficient procedure for the preparation of silica-bound N-propyl triethylenetetramine sulfamic acid (SBPTETSA) by the reaction of silica-bound N-propyl triethylenetetramine (SBPTET) with chlorosulfonic acid in chloroform is described. Silica-bound N-propyl triethylenetetramine sulfamic acid was employed as a recyclable catalyst for the synthesis of 2-amino-4,6-diarylnicotinonitriles from the multi-component reaction of an acetophenone derivative, an aromatic aldehyde, malononitrile, and ammonium acetate under solvent-free conditions at 100°C. The heterogeneous catalyst was recycled for five consecutive runs in the optimized multi-component reaction of 4-chloroacetophenone, 4-chloroenzaldehyde, malononitrile, and ammonium acetate without significant loses to its catalytic activity.
A simple procedure for the preparation of silica-bound N-propyl triethylenetetramine sulfamic acid is described. This heterogeneous solid acid has been employed as a catalyst for the synthesis of 2-amino-4,6-diarylnicotinonitriles at 100°C under solvent-free conditions.Figure optionsDownload as PowerPoint slide
Journal: Chinese Journal of Catalysis - Volume 33, Issues 7–8, July–August 2012, Pages 1312–1317