Effects of simulated microgravity on brain plasticity: A startle reflex habituation study

► This study aimed to verify learning impairment induced by microgravity condition; ► Simulated microgravity was obtained through Head-Down Bed Rest (HDBR); ► Startle reflex habituation was used as a probe for measuring learning deficits; ► HDBR subjects showed a lack of startle habituation compared with sitting controls.