A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease

► Ketogenic diet causes no adverse effects in a mouse model of Huntington's disease. ► Ketogenic diet improves a working memory deficit in female Huntington's model mice. ► Ketogenic diet delays weight loss in a mouse model of Huntington's disease. ► Very low carbohydrate (ketogenic) diets might aid Huntington's disease patients.