کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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59328 | 1419435 | 2015 | 9 صفحه PDF | دانلود رایگان |
Cyclooctatetraenes, including dibenzocyclooctatetraenes, are structurally interesting compounds and are widely used in many areas. Therefore, the development of synthetic methods for such compounds has long been attractive. In this work, a Pd-catalyzed coupling reaction between alkenylbromides and arylbromides has been realized. Multi-substituted 1,4-dibromo-1,3-butadienes and o-bromo-2-(2-bromovinyl)benzenes underwent a Pd-catalyzed cyclodimerization reaction to afford the corresponding multi-substituted cyclooctatetraenes and dibenzo[a,e]cyclooctatetraenes, respectively, in high yields and with excellent regioselectivity.
Graphical AbstractDibenzo[a,e]cyclooctatetraene derivatives are efficiently and regioselectively generated from a palladium-catalyzed [4+4] cyclic homo-coupling of o-bromo-2-(2-bromovinyl)benzenes.Figure optionsDownload as PowerPoint slide
Journal: Chinese Journal of Catalysis - Volume 36, Issue 1, January 2015, Pages 24–32