کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5942 450 2014 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Liquid-solid phase transition alloy as reversible and rapid molding bone cement
ترجمه فارسی عنوان
آلیاژ انتقال آلیاژ مایع جامد به عنوان سیمان ریخته گری سریع و سریع
کلمات کلیدی
فلز مایع، آلیاژ انتقال جامد جامد، سیمان استخوانی قالبگیری برگشت پذیر، جراحی تزریقی، تجدید جراحی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی

Acrylic bone cement has been an essential non-metallic implant used as fixing agent in the cemented total joint arthroplasty (THA). However, the currently available materials based mainly on polymethylmethacrylate (PMMA) still encounter certain limitations, such as time-consuming polymerization, thermal and chemical necrosis and troublesome revision procedure. Here from an alternative way, we proposed for the first time to adopt the injectable alloy cement to address such tough issues through introducing its unique liquid–solid phase transition mechanism. A typical cement along this way is thus made of an alloy Bi/In/Sn/Zn with a specifically designed low melting point 57.5 °C, which enables its rapid molding into various desired shapes with high plasticity and ultimate metallic behaviors. The fundamental characteristics including the mechanical strength, biocompatibility and phase transition-induced thermal effects have been clarified to demonstrate the importance of such alloy as unconventional cement with favorable merits. In addition, we also disclosed its advantage as an excellent contrast agent for radiation imaging on the bone interior structure which is highly beneficial for guiding the surgery and monitoring the therapeutic effects. Particularly, the proposed alloy cement with reversible phase transition feature significantly simplifies the revision of the cement and prosthesis. This study opens the way for employing the injectable alloy materials as reversible bone cement to fulfill diverse clinical needs in the coming time.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 35, Issue 37, December 2014, Pages 9789–9801
نویسندگان
, , , ,