کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5961926 | 1175896 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Why T waves change: A reminiscence and essay
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کلمات کلیدی
CREB4-APAP-14-aminopyridine - 4-آمینوپیریدینTransient outward potassium current - جریان پتاسیم بیرون گذراCardiac memory - حافظه قلبیVentricular pacing - قدم زدن بطن چپcyclic adenosine monophosphate response element binding protein - پروتئین اتصال دهنده عنصر پاسخ آدنوزین مونوفسفره چرخهactivator protein-1 - پروتئین فعال کننده-1
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
The following article is a personal reflection on my study of a subject which has long interested me. The subject is the T wave, and especially the T wave changes occurring as a marker of cardiac memory. My interest evolved over coffees that Mauricio Rosenbaum and I used to share at the Hotel Algonquin during his frequent trips from Buenos Aires to New York. There is something about the Algonquin, whose scarred wooden tabletops carry the imprints of Robert Benchley, Dorothy Parker, and the 1920's New York literati, and there was something about Mauricio-clinician-scientist, friend, and raconteur extraordinaire-that made his repeated challenges to me to “look at cardiac memory before you begin losing your own” irresistible. So began my personal voyage into trying to understand the T wave. My guideposts were the experiments of Wilson and Finch,1 the astute observations of a host of investigators who followed, and Mauricio's iconoclastic insights. The story is far from over â¦Â I doubt I'll see the end of it in my lifetime. But if the beauty of discovery is in the voyage, then it has been - for me - a memorable trip.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Heart Rhythm - Volume 6, Issue 11, Supplement, November 2009, Pages S56-S61
Journal: Heart Rhythm - Volume 6, Issue 11, Supplement, November 2009, Pages S56-S61
نویسندگان
Michael R. MD,