کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5965695 | 1576148 | 2016 | 5 صفحه PDF | دانلود رایگان |
The long-term prognosis of patients with ST-elevation myocardial infarction (STEMI) aged 45Â years or younger and differences according to gender have not been well characterized.MethodsWe included 16,685 consecutive STEMI patients from 2003 to 2012 (67,992 patient-years follow-up) from the Eastern Danish Heart Registry and the Swedish Coronary Angiography and Angioplasty Registry who were treated with primary percutaneous coronary intervention (PCI).ResultsWe identified 1026 (6.2%) patients up to 45Â years of age (mean age: 40.7 vs. 66.3Â years, PÂ <Â 0.001). Patients in the young group were predominantly men (79.7% vs. 71.9%) and smokers (71.2% vs. 44.2%, PÂ <Â 0.001) but with a lower prevalence of hypertension (17.3% vs. 39.3%), hyperlipidemia (18.0% vs. 23.8%), diabetes (9.0% vs. 12.4%) and previous myocardial infarction (6.9% vs. 12.2%, all PÂ <Â 0.001) compared with older patients. Young patients had a 0.8% annual mortality. During the follow-up period 6.3% of young patients died vs. 28.5% of older patients (PÂ <Â 0.001). Both 30-day-mortality (adjusted hazard ratio [HR]Â =Â 0.26, 95% confidence interval [CI]: 0.12-0.54, PÂ <Â 0.001) and mortality after 30Â days and onwards (HRÂ =Â 0.25, CI: 0.17-0.37, PÂ <Â 0.001) were significantly lower in the young group. There was no difference in short-term (HRÂ =Â 0.78, CI: 0.32-1.90, PÂ =Â 0.59) or long-term (HRÂ =Â 0.62, CI: 0.33-1.91, PÂ =Â 0.59) mortality between women and men in the young group (HRÂ =Â 0.79, CI: 0.21-1.80, PÂ =Â 0.39).ConclusionsSTEMI patients, aged 45Â years or younger, have an excellent prognosis after treatment with primary PCI. Long-term annual survival is more than 99% in these patients. Young women with STEMI do not have a worse long-term prognosis than young men with STEMI.
Journal: International Journal of Cardiology - Volume 203, 15 January 2016, Pages 697-701