Three-component, one-pot synthesis of benzo[f]indenoquinoline derivatives catalyzed by poly(4-vinylpyridinium) hydrogen sulfate

7-Aryl-8H-benzo[f]indeno[2,1-b]quinoline-8-one derivatives were synthesized by means of a one-pot condensation of 2-naphthylamine, aromatic aldehydes, and indane-1,3-dione in ethanol under refluxing conditions in the presence of poly(4-vinylpyridinium) hydrogen sulfate, a solid acid catalyst. This method has the advantages of high yield, clean reaction, simple methodology, and short reaction time. The catalyst could be recycled and reused four times without significant loss of activity. The structure of the novel compounds was confirmed by IR, 1H NMR, and 13C NMR spectroscopy and elemental analysis.

Graphical AbstractOne-pot condensation of 2-naphthylamine, aromatic aldehydes, and indane-1,3-dione was performed in refluxing ethanol in the presence of poly(4-vinylpyridinium) hydrogen sulfate as a catalyst. The catalyst could be recycled and reused four times without significant loss of activity.Figure optionsDownload as PowerPoint slide