کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5987097 | 1578220 | 2016 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation
ترجمه فارسی عنوان
رد ریه های ناشی از آنتی بادی: گزارش توافق جامع بین المللی پیوند قلب و ریه
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
Antibody-mediated rejection (AMR) is a recognized cause of allograft dysfunction in lung transplant recipients. Unlike AMR in other solid-organ transplant recipients, there are no standardized diagnostic criteria or an agreed-upon definition. Hence, a working group was created by the International Society for Heart and Lung Transplantation with the aim of determining criteria for pulmonary AMR and establishing a definition. Diagnostic criteria and a working consensus definition were established. Key diagnostic criteria include the presence of antibodies directed toward donor human leukocyte antigens and characteristic lung histology with or without evidence of complement 4d within the graft. Exclusion of other causes of allograft dysfunction increases confidence in the diagnosis but is not essential. Pulmonary AMR may be clinical (allograft dysfunction which can be asymptomatic) or sub-clinical (normal allograft function). This consensus definition will have clinical, therapeutic and research implications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Heart and Lung Transplantation - Volume 35, Issue 4, April 2016, Pages 397-406
Journal: The Journal of Heart and Lung Transplantation - Volume 35, Issue 4, April 2016, Pages 397-406
نویسندگان
Deborah J. MD, Allan R. MBBS, MD, Christina BA, MBA, John MD, Christian MD, FCCP, Gerald J. MD, Ramsey MD, Don Jr., MD, MS, Desley MBBS, PhD, Nancy L. PhD, D(ABHI), Laurie D. MD, Stuart MD, PhD, Dolly PhD, Geert MD, PhD, Glen MBBS, PhD, Roger D. MD, MPH,