کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6006260 1184678 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Safety of 5 kHz tACS
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Safety of 5 kHz tACS
چکیده انگلیسی

BackgroundSinusoidal transcranial alternating current stimulation (tACS) at 5 kHz applied for 10 min at 1 mA intensity over the hand area of the primary motor cortex (M1) results in sustained changes in cortical excitability as previously demonstrated.ObjectiveHere we have assessed safety aspects of this stimulation method by measuring neuron-specific enolase (NSE) levels, examining electroencephalogram (EEG) traces and analyzing anatomical data by using magnetic resonance imaging (MRI).MethodsAltogether 18 healthy volunteers participated in the study. tACS was applied at 5 kHz for a duration of 10 min over the left M1 at an intensity of 1 mA.ResultsAfter stimulation no significant changes were detected in NSE levels, no structural alterations were observed in the anatomical scans and no pathological changes were found in the EEG recordings.ConclusionsOur data imply that the application of tACS is safe at least within these parameters and with these applied protocols.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Stimulation - Volume 7, Issue 1, January–February 2014, Pages 92-96
نویسندگان
, , , , , , , ,