کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6007592 1184953 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Atypical valuation of monetary and cigarette rewards in substance dependent smokers
ترجمه فارسی عنوان
ارزیابی غیرمستقیم پاداش های پولی و سیگاری در افراد سیگاری وابسته به مواد
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
چکیده انگلیسی


- Non-drug relative to drug-related rewards were compared using the reward positivity.
- Cigarette relative to monetary rewards elicited a larger reward positivity.
- Obtaining drug-related rewards engages the anterior cingulate cortex (ACC) to exert control over behaviors in substance dependent (SD) individuals.

ObjectiveSubstance dependent (SD) relative to non-dependent (ND) individuals exhibit an attenuated reward positivity, an electrophysiological signal believed to index sensitivity of anterior cingulate cortex (ACC) to rewards. Here we asked whether this altered neural response reflects a specific devaluation of monetary rewards relative to drug-related rewards by ACC.MethodsWe recorded the reward positivity from SD and ND individuals who currently smoke, following an overnight period of abstinence, while they engaged in two feedback tasks. In a money condition the feedback indicated either a monetary reward or no reward, and in a cigarette condition the feedback indicated either a drug-related reward or no reward.ResultsOverall, cigarette relative to monetary rewards elicited a larger reward positivity. Further, for the subjects who engaged in the money condition first, the reward positivity was smaller for the SD compared to the ND participants, but for the subjects who engaged in the cigarette condition first, the reward positivity was larger for the SD compared to the ND participants.ConclusionsOur results suggest that the initial category of feedback “primed” the response of the ACC to the alternative feedback type on subsequent trials, and that SD and ND individuals responded differently to this priming effect.SignificanceWe propose that for people who misuse addictive substances, the prospect of obtaining drug-related rewards engages the ACC to exert control over extended behaviors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurophysiology - Volume 127, Issue 2, February 2016, Pages 1358-1365
نویسندگان
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